The AIRR Knowledge Commons (AKC) is being established by merging data from existing, community-backed repositories and applying existing and novel, cross-cutting knowledge-generation algorithms to the integrated data. The AKC currently includes (1) data from the AIRR Data Commons, which contains >10,000 repertoires with billions of AIRs, integrated with (2) AIR germline allele, genotype, haplotype, and population genetic data from the Open Germline Receptor Database and VDJbase, and (3) AIR specificity data from the Immune Epitope Database and Immune Receptor Antigen Database.
VDJServer was established with funding from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) under R01A1097403. VDJServer received funding from the European Union’s Horizon 2020 Research and Innovation Program (#825821) and is currently funded by NIAID under U24AI177622.
iReceptor was established with funding from CANARIE Network Enabled Platforms Program, the Canada Foundation for Innovation (CFI), the British Columbia Knowledge Development Fund (BCKDF), the Canadian Institute for Health Research, the European Union’s Horizon 2020 research and innovation programme (grant agreement No 825821), and Simon Fraser University. iReceptor currently receives funding under U24AI177622.
VDJBase is funded by the Israel Science Foundation [2940/21], SeqSpace DSI VATAT grant, and NIAID under R24 AI162317-02 and U24AI177622.
OGRDB receives funding under U24AI177622.
The IEDB is funded by NIAID under contract 75N93019C00001. This is the IEDB’s third contract with NIAID. It was previously funded by NIAID under contracts HHSN266200400006C (IEDB 1) and HHSN272201200010C (IEDB 2). The IEDB is also funded under U24AI177622.
IRAD
IRAD is funded by NIAID under U24AI177622 and by a grant from the Center for Pediatric Genomics (CpG) from the Cincinnati Children’s Hospital Medical Center.